Uropepsin Excretion by Man. Iii. Uropepsin Excretion by Patients with Peptic Ulcer and Other Lesions of the Stomach.

In preceding papers (1, 2) we have outlined results which indicate that uropepsin excretion may serve as a useful index of the rate of the "intrinsic" or endocrine-like activity of the pepsinogen-secreting cells of the gastric mucosa. Data were also presented concerning the uropepsin excretion patterns of healthy, adult male subjects. Since various lesions of the stomach and duodenum are associated with either an increase or a decrease in the rate of gastric activity, the uropepsin excretions of patients suffering from a variety of conditions affecting the gastrointestinal tract were investigated.